Recombinant Anti-Vitronectin Antibody, Rabbit Monoclonal

RRID Number: AB_2860511
EliteRmab®, manufactured by recombinant technology
1/1
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Recombinant Anti-Vitronectin Antibody, Rabbit Monoclonal 产品信息

产品名称
Recombinant Anti-Vitronectin Antibody, Rabbit Monoclonal
经验证的应用
ELISA,IHC-P
交叉反应
Reacts with: Mouse
特异性
Mouse Vitronectin
免疫原
Recombinant Mouse Vitronectin / VTN protein (Catalog#50585-M08H)
制备方法
This antibody was obtained from a rabbit immunized with purified, recombinant Mouse Vitronectin / VTN (rM Vitronectin / VTN; Catalog#50585-M08H; NP_035837.1; Met1-Lys478).
来源
Monoclonal Rabbit IgG Clone #019
纯化
Protein A
缓冲液
0.2 μm filtered solution in PBS
偶联物
Unconjugated
状态
Liquid
运输方式
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
储存条件
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Recombinant Anti-Vitronectin Antibody, Rabbit Monoclonal 经验证的应用

应用 推荐稀释比/用量
ELISA 1:5000-1:10000
IHC-P 1:100-1:500
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Recombinant Anti-Vitronectin Antibody, Rabbit Monoclonal 图片

Immunochemical staining of mouse VTN in mouse liver with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections).

Recombinant Anti-Vitronectin Antibody, Rabbit Monoclonal: 别称

Anti-AI256434 Antibody; Anti-Vn Antibody

Vitronectin 背景信息

Vitronectin, also known as VTN, is a member of the pexin family. It is an abundant glycoprotein found in serum the extracellular matrix and promotes cell adhesion and spreading. Vitronectin is a secreted protein and exists in either a single chain form or a cleaved, two chain form held together by a disulfide bond. Vitronectin is a plasma glycoprotein implicated as a regulator of diverse physiological process, including blood coagulation, fibrinolysis, pericellular proteolysis, complement dependent immune responses, and cell attachment and spreading. Because of its ability to bind platelet glycoproteins and mediate platelet adhesion and aggregation at sites of vascular injury, vitronectin has become an important mediator in the pathogenesis of coronary atherosclerosis. As a multifunctional protein with a multiple binding domain, Vitronectin interacts with a variety of plasma and cell proteins. Vitronectin binds multiple ligands, including the soluble vitronectin receptor. It may be an independent predictor of adverse cardiovascular outcomes following acute stenting. Accordingly, Vitronectin is suggested to be involved in hemostasis, cell migration, as well as tumor malignancy.
全称
vitronectin
参考文献
  • Ekmeki OB, et al. (2006) Vitronectin in atherosclerotic disease. Clin Chim Acta. 368(1-2): 77-83.
  • Derer W, et al. (2009) Vitronectin concentrations predict risk in patients undergoing coronary stenting. Circ Cardiovasc Interv. 2(1): 14-9.
  • Heyman L, et al. (2010) Mesothelial vitronectin stimulates migration of ovarian cancer cells. Cell Biol Int. 34(5): 493-502.
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