Anti-C-Reactive Protein Antibody, Rabbit Polyclonal

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Anti-C-Reactive Protein Antibody, Rabbit Polyclonal 产品信息

产品名称
Anti-C-Reactive Protein Antibody, Rabbit Polyclonal
经验证的应用
ELISA
交叉反应
Reacts with: Rat
特异性
Rat C-Reactive Protein
免疫原
Recombinant Rat CRP / C-Reactive Protein protein (Catalog#80041-R08H)
制备方法
Produced in rabbits immunized with purified, recombinant Rat CRP / C-Reactive Protein (rR CRP / C-Reactive Protein; Catalog#80041-R08H; NP_058792.1; Met 1-Ser 230). CRP / C-Reactive Protein specific IgG was purified by Rat CRP / C-Reactive Protein affinity chromatography.
来源
Polyclonal Rabbit IgG
纯化
Protein A & Antigen Affinity
缓冲液
0.2 μm filtered solution in PBS
偶联物
Unconjugated
状态
Liquid
运输方式
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
储存条件
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Anti-C-Reactive Protein Antibody, Rabbit Polyclonal 经验证的应用

应用 推荐稀释比/用量
ELISA 1:5000-1:10000
Please Note: Optimal concentrations/dilutions should be determined by the end user.

C-Reactive Protein 背景信息

C-reactive protein (CRP) is synthesized by the liver in response to factors released by fat cells. It is a member of the pentraxin family of proteins. The levels of CRP rise in response to inflammation. Human C-reactive protein (CRP) is the classical acute phase reactant, the circulating concentration of which rises rapidly and extensively in a cytokine-mediated response to tissue injury, infection and inflammation. Serum CRP values are routinely measured, empirically, to detect and monitor many human diseases. However, CRP is likely to have important host defence, scavenging and metabolic functions through its capacity for calcium-dependent binding to exogenous and autologous molecules containing phosphocholine (PC) and then activating the classical complement pathway. CRP may also have pathogenic effects and the recent discovery of a prognostic association between increased CRP production and coronary atherothrombotic events is of particular interest.
全称
C-reactive protein, pentraxin-related
参考文献
  • Pepys MB. et al., 2003, J Clin Invest. 111 (12): 1805-12.
  • Thompson D. et al., 1999, Structure. 7(2): 169-77.
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