Recombinant Anti-CD48 Antibody (FITC), Rabbit Monoclonal

EliteRmab®, manufactured by recombinant technology
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Recombinant Anti-CD48 Antibody (FITC), Rabbit Monoclonal 产品信息

产品名称
Recombinant Anti-CD48 Antibody (FITC), Rabbit Monoclonal
经验证的应用
FCM
交叉反应
Reacts with: Rat
特异性
Rat CD48
免疫原
Recombinant Rat CD48 / SLAMF2 protein (Catalog#80286-R08H)
制备方法
This antibody was obtained from a rabbit immunized with purified, recombinant Rat CD48 / SLAMF2 (rR CD48 / SLAMF2; Catalog#80286-R08H; P10252; Met1-Arg216) and conjugated with FITC under optimum conditions, the unreacted FITC was removed.
来源
Monoclonal Rabbit IgG Clone #002
纯化
Protein A
缓冲液
Aqueous solution containing 0.5% BSA and 0.09% sodium azide
偶联物
FITC
浓度
10 μl/Test, 0.1 mg/ml
状态
Liquid
运输方式
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
储存条件
This antibody can be stored at 2℃-8℃ for twelve months without detectable loss of activity. Protected from prolonged exposure to light. Do not freeze ! Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.

Recombinant Anti-CD48 Antibody (FITC), Rabbit Monoclonal 图片

Flow cytometric analysis of Rat CD48 expression on rat splenocytes. SD splenocytes were stained with FITC-conjugated anti-Rat CD48. The histogram were derived from gated events with the forward and side light-scatter characteristics of intact cells.

CD48 背景信息

Cluster of Differentiation 48 (CD48), also known as SLAMF2, BCM-1 and BLAST-1, is a GPI-linked protein belonging to the CD2 subfamily of immunoglobulin superfamily molecules. CD2 and 2B4 (CD244) are known ligands for CD48. CD48 protein is expressed on most lineage-committed hematopoietic cells but not on hematopoietic stem cells or multipotent hematopoietic progenitors. CD48 protein performs biological functions in a variety processes including adhesion, pathogen recognition, cellular activation, and cytokine regulation, and emerges as a critical effector molecule in immune responses.
全称
CD48 molecule
研究领域
参考文献
  • Messmer B, et al. (2006) CD48 stimulation by 2B4 (CD244)-expressing targets activates human NK cells. J Immunol. 176(8): 4646-50
  • Milstein O, et al. (2008) Nanoscale increases in CD2-CD48-mediated intermembrane spacing decrease adhesion and reorganize the immunological synapse. J Biol Chem. 283(49): 34414-22.
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