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To achieve certain level of therapeutic effects in vivo, an antibody needs to reach a minimum affinity level. However, in some cases it may not be easy to screening for antibodies that possess the right biological function and have very high antigen binding affinity in the same time. In this case, improving an existing antibody's antigen-binding affinity might be the best approach one could take the antibody into clinical development. In some other cases, an antibody's affinity can drop significantly after humanization. Hence increase the humanized antibody's affinity back to the level before its humanization may be necessary. Affinity maturation is a common strategy to improve an antibody's antigen-binding affinity.
With its in-house phage-display technology and molecule biology techniques, Sino Biological has mastered experience and expertise in antibody affinity maturation. Our transient transfection platform can further support rapid and high-throughput antibody production. Our antibody affinity maturation service can be tailor-designed to meet your specific needs and it is fast, reliable, and affordable. Contact us now to learn more on our antibody affinity maturation service. Our service team will get back to you quickly.
How to Submit a Request for Antibody Humanization & Affinity Maturation Service?
If you are interested in using our antibody humanization and affinity maturation services to support your antibody discovery and development program, please contact us by leaving an on-line message or send us your detailed request to CROfirstname.lastname@example.org. Based on the quantity and quality requirement of your request, a formal quote will be send back to you for your review, comment, and/or acceptance.