• Cutting-edge technologies
• Most reliable partner
• Unmatched experience:>10,000 Mabs,>6000 Proteins
• Superior quality of products & services
• Unmatched speed of production
• Unmatched cost-saving
Mouse and rabbit antibody needs to be humanized to minimize its immunogenicity and improve its pharmacokinetics in vivo. The humanization technology was initially invented over 20 years ago and has been gradually improved and optimized over the last two decades both in academic and industrial research. Sino Biological has spent many years developing and optimizing antibody humanization. With the support of computer aided protein and antibody structure modeling, our antibody humanization process can be greatly simplified and the duration shortened significantly. Our powerful in house high-throughput antibody production capability further reduces the cycle time of antibody humanization.
Sino Biological's antibody humanization experience covers not only mouse antibody but also rabbit monoclonal antibody. Our record speed for antibody humanization was 2 weeks, including antibody molecule structure modification, high-throughput antibody production by transient transfection, antibody characterization and bioactivity measurement.
Our full service antibody humanization can start from mouse or rabbit hybridoma cells. We are experienced in cloning the mouse and rabbit antibody genes (VL and VH) from the hybridoma cells, and construct full mouse and rabbit monoclonal antibodies with a preferred antibody Fc subtype chosen by customer.
Mouse and rabbit monoclonal antibody humanization is an art work that requires many years of technology development and repeated practice as well as strong antibody production support. Our professional team is at your service and ready to support your antibody discovery efforts.
How to Submit a Request for Antibody Humanization Service?
If you are interested in using our antibody humanization services to support your antibody discovery and development program, please contact us by leaving an on-line message or send us your detailed request to CROfirstname.lastname@example.org. Based on the quantity and quality requirement of your request, a formal quote will be send back to you for your review, comment, and/or acceptance.