The innate immune system is the phylogenically oldest component of the human immune system. Although it is ancient, the innate immune system is highly complex and consists of barriers to infection (epithelia of skin, gastrointestinal, respiratory, genitourinary tracts), antimicrobial peptides and proteins, humoral components (i.e. complement and opsonins) and cellular components (i.e. neutrophils, monocytes/macrophages, dendritic cells, and innate lymphoid cells). Innate immunity serves as the front line of host defense and plays an essential role in preventing infection while tolerating normal host flora. Defects in innate immunity are associated with invasive, life-threatening infection. Inappropriate activation of the innate immune system can lead to autoinflammatory states. The innate immune system directs the subsequent development of adaptive immune responses. Its proper function is thus critical for health.
Sino Biological lists the classification tree of Innate Immunity, click to see all the related molecules/targets and research reagents of them.
Innate Immunity
Innate Immunity
Coagulation
Coagulation
Coagulation Cascade Protease Inhibitors
Coagulation Cascade Protease Inhibitors
Coagulation Cascade Proteases
Coagulation Cascade Proteases
Coagulation Factors
Coagulation Factors
Other Coagulation Cascade Molecules
Other Coagulation Cascade Molecules
Plasmin/Plasminogen and Kallikrein/Kinin Systems
Plasmin/Plasminogen and Kallikrein/Kinin Systems
Complement System
Complement System
Alternative Complement Pathway
Alternative Complement Pathway
Classical Complement Pathway
Classical Complement Pathway
Complement Regulatory Proteins
Complement Regulatory Proteins
Granulocyte Markers
Granulocyte Markers
Lysosomal Enzymes
Lysosomal Enzymes
Monocyte/Macrophage
Monocyte/Macrophage
Co-stimulatory Molecules
Co-stimulatory Molecules
Macrophage Markers
Macrophage Markers
Monocyte Markers
Monocyte Markers
Osteoblast and Osteoclast Markers
Osteoblast and Osteoclast Markers
Scavenger Receptors
Scavenger Receptors
Natural Killer Cell (NK Cell)
Natural Killer Cell (NK Cell)
Pattern Recognition Receptors
Pattern Recognition Receptors
C-type Lectin Receptors
C-type Lectin Receptors
NOD-like Receptors and the Inflammasome
NOD-like Receptors and the Inflammasome
RIG-I-like Receptors
RIG-I-like Receptors
