ADRB3 Antibodies, cDNA Clones Research Reagents

ADRB3 (Adrenoceptor Beta 3) is a protein coding gene located on human chromosome 8p11.23. ADRB3 is also known as BETA3AR. The human ADRB3 gene encodes a 43519 Da protein containing 408 amino acids. The ADRB3 protein is biasedly expressed in ovary, placenta and other tissues. Among its related pathways are Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins, and Signaling by GPCR. ADRB3 is related to G protein-coupled receptor activity and epinephrine binding. ENSG00000285880 is an important paralog of ADRB3 gene. ADRB3 is associated with some diseases, including Body Mass Index Quantitative Trait Locus 11 and Low Compliance Bladder.

ADRB3 Antibody (1)

    ADRB3 cDNA Clone (1)

    NM_000025.2

    In expression vector

    ADRB3 分子背景

    beta3-Adrenergic receptor (ADRB3) Trp64Arg polymorphism is associated with atherogenic risk factors that include weight gain, insulin resistance, and diabetes. Habitual exercise brings higher cardiorespiratory fitness and results in the amelioration of atherosclerotic risk factors. Presence of the beta3-Adrenergic receptor (ADRB3) gene Trp64Arg (T64A) polymorphism may be associated with an increased susceptibility for essential hypertension (EH). The beta3-adrenergic receptor (ADRB3) regulates thermogenesis and lipolysis in brown and white adipose tissue. ADRB3 plays a critical role in the regulation of energy metabolism in mammals. Polymorphism in the ovine ADRB3 gene has been reported to be associated with birth weight, growth rate, carcass composition, and cold survival.

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