AKR1C2 Proteins, cDNA Clones Research Reagents

All AKR1C2 reagents are produced in house and quality controlled, including 15 AKR1C2 Gene, 1 AKR1C2 Protein, 1 AKR1C2 qPCR. All AKR1C2 reagents are ready to use.

AKR1C2 Protein (1)

    AKR1C2 cDNA Clone (15)

    BC007024

    克隆载体 cDNA 产品

    In lentiviral vector

    AKR1C2 qPCR Primer (1)

    AKR1C2 分子背景

    AKR1C2 is a member of the aldo/keto reductase superfamily, which consists of more than 4 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. AKR1C2 gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 1p15-p14. Three transcript variants encoding two different isoforms have been found for AKR1C2 gene.

    AKR1C2 参考文献

    • Jin Y. et al., 2011, Biochem J. 437 (1): 53-61.
    • Veilleux A. et al., 2012, Am J Physiol Endocrinol Metab. 302 (8): E941-9.
    • Kuang P. et al., 2012, Lung Cancer. 77 (2): 427-32.

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