AKR1C2 Proteins, cDNA Clones Research Reagents

All AKR1C2 reagents are produced in house and quality controlled, including 15 AKR1C2 Gene, 1 AKR1C2 Protein, 1 AKR1C2 qPCR. All AKR1C2 reagents are ready to use.

AKR1C2 Protein (1)

    AKR1C2 cDNA Clone (15)


    克隆载体 cDNA 产品

    In lentiviral vector

    AKR1C2 qPCR Primer (1)

    AKR1C2 分子背景

    AKR1C2 is a member of the aldo/keto reductase superfamily, which consists of more than 4 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. AKR1C2 gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 1p15-p14. Three transcript variants encoding two different isoforms have been found for AKR1C2 gene.

    AKR1C2 参考文献

    • Jin Y. et al., 2011, Biochem J. 437 (1): 53-61.
    • Veilleux A. et al., 2012, Am J Physiol Endocrinol Metab. 302 (8): E941-9.
    • Kuang P. et al., 2012, Lung Cancer. 77 (2): 427-32.

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