Annexin VI/ANXA6 Proteins, Antibodies, cDNA Clones Research Reagents

All Annexin VI/ANXA6 reagents are produced in house and quality controlled, including 3 Annexin VI/ANXA6 Antibody, 60 Annexin VI/ANXA6 Gene, 1 Annexin VI/ANXA6 IP Kit, 1 Annexin VI/ANXA6 Protein, 2 Annexin VI/ANXA6 qPCR. All Annexin VI/ANXA6 reagents are ready to use.

Annexin VI/ANXA6 Protein (1)

    Annexin VI/ANXA6 Antibody (3)

      Annexin VI/ANXA6 cDNA Clone (60)

      NM_001155.4

      克隆载体 cDNA 产品

      In lentiviral vector

      NM_001110211.1

      克隆载体 cDNA 产品

      In lentiviral vector

      XM_002710760.1

      克隆载体 cDNA 产品

      In lentiviral vector

      XM_002710319.1

      克隆载体 cDNA 产品

      In lentiviral vector

      Annexin VI/ANXA6 分子背景

      Annexin A6, also known as ANXA6 or ANXAⅥ, belongs to a family of Ca2+-dependent membrane and phospholipid binding proteins. Members of this family have been implicated in membrane-related events along exocytotic and endocytotic pathways. Annexin 6 is phosphorylated in vivo associated with cell growth. Annexin 6 was not phosphorylated in quiescent cells, but was phosphorylated on serine and to a lesser extent threonine, several hours following cell stimulation. Experiment has revealed the presence of annexin A6 on the cell surface of variety cells as putative receptors and / or binding proteins for chondroitin sulfate proteoglycans, helping cells to bind with this extracellular matrix glycosaminoglycan chondroitin sulfate which is related to the cell-substratum adhesion. A post-tranlational modification other than direct protein phosphorylation may influence the activity of annexin6 and provide evidence linking cell growth with regulation of annexin 6 function.

      Annexin VI/ANXA6 参考文献

      • Takagi H, et al. (2002) Annexin 6 is a putative cell surface receptor for chondroitin sulfate chains. J Cell Sci. 115 (16): 3309-18.
      • Moss SE, et al. (1992) A growth-dependent post-translational modification of annexin VI. Biochim Biophys Acta. 1160 (1): 120-6.
      • Song G, et al. (1998) Altered cardiac annexin mRNA and protein levels in the left ventricle of patients with end-stage heart failure. J Mol Cell Cardio. 30 (3): 443-51.

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