Aquaporin 9/AQP9 Antibodies, cDNA Clones Research Reagents

All Aquaporin 9/AQP9 reagents are produced in house and quality controlled, including 1 Aquaporin 9/AQP9 Antibody, 41 Aquaporin 9/AQP9 Gene, 2 Aquaporin 9/AQP9 qPCR. All Aquaporin 9/AQP9 reagents are ready to use.

Aquaporin 9/AQP9 Antibody (1)

    Aquaporin 9/AQP9 cDNA Clone (41)

    BC026258

    克隆载体 cDNA 产品

    In lentiviral vector

    NM_022026.3

    克隆载体 cDNA 产品

    In lentiviral vector

    AF016406.1

    克隆载体 cDNA 产品

    In lentiviral vector

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    Aquaporin 9/AQP9 分子背景

    Aquaporins (AQPs) are a family of small integral membrane proteins made up of 6 hydrophobic, a-helical, membrane-spanning domains surrounding a highly selective aqueous pore. AQP3, AQP7, and AQP9, termed aqua-glyceroporins, are known to be involved in the transport of water, glycerol, and other small molecules. AQP3 and AQP9 facilitate both transcellular osmotic water flow and glycerol transport as pore-like passive transporters in the keratinocytes of oral epithelia, and may play a key role in not only hydration and the permeability barrier, but also cell proliferation, differentiation, migration, development, and wound healing by generating ATP. Aquaporin-9 (AQP9) is a membrane protein channel that is permeable to a range of small solutes, including glycerol, urea and nucleobases. Aquaporin-9 (AQP9) expression is associated with arsenic sensitivity in leukemia cells. AQP9 might be a novel predictor for the benefit of 5-FU-based chemotherapy in CRC. The identification of AQP9-induced tumor sensitivity to 5-FU highlights the role of AQP9 in regulating chemosensitivity in CRC. aquaporin 9 (AQP9) in the prostate was strictly upregulated by androgen and may represent a novel therapeutic target for several cancers. AQP9 molecular expression mediated by insulin in a concentration-dependent manner in human placenta and provide new evidence that in preeclamptic placentas the mechanisms of insulin signaling may be altered, producing an overexpression of AQP9 that does not correlate with an increase in its functionality.

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