BCL6 Proteins, Antibodies, cDNA Clones Research Reagents

All BCL6 reagents are produced in house and quality controlled, including 2 BCL6 Antibody, 15 BCL6 Gene, 1 BCL6 Protein, 1 BCL6 qPCR. All BCL6 reagents are ready to use.

BCL6 Protein (1)

    BCL6 Antibody (2)

      BCL6 cDNA Clone (15)


      克隆载体 cDNA 产品

      In lentiviral vector

      BCL6 qPCR Primer (1)


      BCL6 分子背景

      The protein encoded by this gene is an evolutionarily conserved 95-kDa protein containing six C-terminal zinc-finger motifs and an N-terminal POZ domain. It has been reported that BCL-6 is present in DNA-binding complexes in nuclear extracts from various B-cell lines. There are many relationships between non-Hodgkin's lymphoma, diffuse large cell lymphoma and BCL6’s translocations. BCL6 can repress transcription from promoters linked to its DNA target sequence and this activity is dependent upon specific DNA-binding and the presence of an intact N-terminal half of the protein.

      BCL6 参考文献

      • Ye BH, et al. (1997) The BCL-6 proto-oncogene controls germinal-centre formation and Th2-type inflammation. Nature Genetics. 16: 161-70.
      • Seyfert VL, et al. (1996) Transcriptional repression by the proto-oncogene BCL-6. Oncogene. 12 (11) : 2331-42.
      • Chang CC, et al. (1996) BCL-6, a POZ/zinc-finger protein, is a sequence-specific transcriptional repressor. PNAS. 93 (14): 6947-52.

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