BDNF Proteins, Antibodies, cDNA Clones Research Reagents

All BDNF reagents are produced in house and quality controlled, including 3 BDNF Antibody, 41 BDNF Gene, 2 BDNF Lysate, 2 BDNF Protein, 2 BDNF qPCR. All BDNF reagents are ready to use.

BDNF Protein (2)

    BDNF Antibody (3)

      BDNF cDNA Clone (41)

      NM_001709.3

      克隆载体 cDNA 产品

      In lentiviral vector

      NM_001048139.1

      克隆载体 cDNA 产品

      In lentiviral vector

      NM_001002975.1

      克隆载体 cDNA 产品

      In lentiviral vector

      BDNF Lysate (2)

        BDNF 分子背景

        BDNF is a member of the nerve growth factor family. It is highly expressed in hippocampus, amygdala, cerebral cortex and cerebellum. It also can be detected in heart, lung, skeletal muscle, testis, prostate and placenta. BDNF is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. During development, BDNF promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. It participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. It functions as the major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.

        BDNF 参考文献

        • Zigova T, et al. (1998) Intraventricular administration of BDNF increases the number of newly generated neurons in the adult olfactory bulb. Mol Cell Neurosci. 11(4):234-45.
        • Acheson A, et al. (1995) A BDNF autocrine loop in adult sensory neurons prevents cell death. Nature 374(6521):450-3.
        • Bekinschtein P, et al. (2008) BDNF is essential to promote persistence of long-term memory storage. Proc Natl Acad Sci. 105(7):2711-6.

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