BMP10 Antibodies, cDNA Clones Research Reagents

All BMP10 reagents are produced in house and quality controlled, including 1 BMP10 Antibody, 39 BMP10 Gene, 2 BMP10 qPCR. All BMP10 reagents are ready to use.

BMP10 Antibody (1)

    BMP10 cDNA Clone (39)

    NM_014482.1

    克隆载体 cDNA 产品

    In lentiviral vector

    NM_001031824.1

    克隆载体 cDNA 产品

    In lentiviral vector

    XM_001096299.1

    克隆载体 cDNA 产品

    In lentiviral vector

    BMP10 qPCR Primer (2)

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    BMP10 分子背景

    Bone morphogenetic proteins (BMPs) control the development of diverse tissues during embryogenesis. Bone morphogenetic protein-10 (BMP10), a novel member of the bone morphogenetic protein (BMP) family, has been indicated as a possible tumour suppressor in prostate and breast cancer. Hypertension induced expression of prohypertrophic BMP10, and the hypertrophic effect of BMP10 was modulated, at least in part, by its binding to Tcap at the Z disc. Expression of BMP10 protein is reduced in cancer cells of bladder tumours. Overexpression of BMP10 has an inhibitory effect on the growth, adhesion, and migration of bladder cancer cells in vitro. This would suggest a potential tumour suppressor role of BMP10 in bladder cancer. Bone morphogenetic protein (BMP)9 and BMP10 are high affinity ligands for activin receptor-like kinase 1 (ALK1), a type I BMP receptor mainly expressed on vascular endothelial cells (ECs). ALK1-mediated BMP9/BMP10 signalling pathways have emerged as essential in EC biology and angiogenesis.

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