CD157 Proteins, Antibodies, cDNA Clones, ELISA Kits Research Reagents

All CD157 reagents are produced in house and quality controlled, including 16 CD157 Antibody, 2 CD157 ELISA, 39 CD157 Gene, 1 CD157 IP Kit, 4 CD157 Lysate, 4 CD157 Protein, 3 CD157 qPCR. All CD157 reagents are ready to use.

CD157 Protein (4)

    CD157 Antibody (16)

      CD157 ELISA 试剂盒(即用型)& ELISA 抗体对套装(非即用型)(2)

      CD157 cDNA Clone (39)

      NM_004334.2

      克隆载体 cDNA 产品

      In lentiviral vector

      NM_009763.3

      克隆载体 cDNA 产品

      In lentiviral vector

      NM_030848.1

      克隆载体 cDNA 产品

      In lentiviral vector

      CD157 Lysate (4)

        CD157 分子背景

        The cluster of differentiation (CD) system is commonly used as cell markers in immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD157, also known as ADP-ribosyl cyclase 2, is an ectoenzyme sharing several characteristics with ADP-ribosyl cyclase CD38. CD157 was originally identified as a bone marrow stromal cell molecule (BST-1) with a glycosylphosphatidylinositol (GPI) anchor to bind to the cell surface. CD157 is prevalently expressed by cells of the myeloid lineage. CD157 could act as a receptor with signal transduction capability. Further, it regulates calcium homeostasis and promotes polarization in neutrophils and mediates superoxide (O2−) production in the human U937 myeloid line.

        CD157 参考文献

        • Zola H, et al. (2007) CD molecules 2006-human cell differentiation molecules. J Immunol Methods. 318 (1-2): 1-5.
        • Ho IC, et al. (2009) GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat Rev Immunol. 9 (2): 125-35.
        • Matesanz-Isabel J, et al. (2011) New B-cell CD molecules. Immunology Letters.134 (2): 104-12.
        • Malavasi F, et al. (2006) CD38 and CD157 as Receptors of the Immune System: A Bridge Between Innate and Adaptive Immunity. Molecular Medicine. 12 (11-12): 334-41.
        • Ortolan E, et al. (2002) CD157, the janus of CD38 but with a unique personality. Cell Biochemistry and Function. 20 (4): 309-22.

        Note: Flag® is a registered trademark of Sigma Aldrich Biotechnology LP. It is used here for informational purposes only.