CFHR1 Proteins, Antibodies, cDNA Clones Research Reagents

All CFHR1 reagents are produced in house and quality controlled, including 2 CFHR1 Antibody, 14 CFHR1 Gene, 1 CFHR1 Lysate, 1 CFHR1 Protein. All CFHR1 reagents are ready to use.

CFHR1 Protein (1)

    CFHR1 Antibody (2)

      CFHR1 cDNA Clone (14)

      NM_002113.2

      In expression vector

      NM_015780.2

      克隆载体 cDNA 产品

      In lentiviral vector

      CFHR1 Lysate (1)

        CFHR1 分子背景

        CFHR1 is a secreted protein belonging to the complement factor H protein family.The human complement factor H protein family consists of the complement and immune regulators factor H, the factor H-like protein 1(FHL-1) and five factor H-related proteins (CFHR-1 to -5). Members of the H-related protein family are exclusively composed of individually folded protein domains, termed short consensus repeats (SCRs) or complement control modules. CFHR1 binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. CFHR1 might be involved in complement regulation. It can associate with lipoproteins and may play a role in lipid metabolism.

        CFHR1 参考文献

        • Martnez-Barrica, et al. (2012) Relevance of complement factor H-related 1 (CFHR1) genotypes in age-related macular degeneration. Invest Ophthalmol Vis Sci. 53(3):1087-94.
        • Leban N, et al. (2012) Factor H and CFHR1 polymorphisms associated with atypical Haemolytic Uraemic Syndrome (aHUS) are differently expressed in Tunisian and in Caucasian populations. Int J Immunogenet. 39(2):110-3.
        • Kubista KE, et al. (2011) Copy number variation in the complement factor H-related genes and age-related macular degeneration. Int J Immunogenet. Mol Vis. 17:2080-92.

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