CLEC5A Proteins, Antibodies, cDNA Clones Research Reagents

All CLEC5A reagents are produced in house and quality controlled, including 3 CLEC5A Antibody, 27 CLEC5A Gene, 3 CLEC5A Lysate, 3 CLEC5A Protein, 1 CLEC5A qPCR. All CLEC5A reagents are ready to use.

CLEC5A Protein (3)

    CLEC5A Antibody (3)

      CLEC5A cDNA Clone (27)

      NM_001301167.1

      In expression vector

      NM_001109377.1

      克隆载体 cDNA 产品

      In lentiviral vector

      XM_001085243.2

      克隆载体 cDNA 产品

      In lentiviral vector

      CLEC5A qPCR Primer (1)

      CLEC5A Lysate (3)

        CLEC5A 分子背景

        CLEC5A, also known as MDL1 and MDL-1, is a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. CLEC5A with dnax-activation protein 12 and may play a role in cell activation. It also functions as a positive regulator of osteoclastogenesis. CLEC5A acts as a key regulator of synovial injury and bone erosion during autoimmune joint inflammation .The binding of dengue virus to CLEC5A triggers signaling through the phosphylation of TYROBP, this interaction does not result in viral entry, but stimulates proinflammatory cytokine release.

        CLEC5A 参考文献

        • Chen ST. et al., 2008, Nature. 453 (7195): 672-6.
        • Davila S. et al., 2010, Genes Immun. 11 (3): 232-8.
        • Hillier LW. et al., 2003, Nature. 424 (6945): 157-64.

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