CNTFR Proteins, Antibodies, cDNA Clones Research Reagents

All CNTFR reagents are produced in house and quality controlled, including 3 CNTFR Antibody, 38 CNTFR Gene, 2 CNTFR Lysate, 2 CNTFR Protein, 2 CNTFR qPCR. All CNTFR reagents are ready to use.

CNTFR Protein (2)

    CNTFR Antibody (3)

      CNTFR cDNA Clone (38)


      克隆载体 cDNA 产品

      In lentiviral vector


      克隆载体 cDNA 产品

      In lentiviral vector

      CNTFR qPCR Primer (2)

      CNTFR Lysate (2)

        CNTFR 分子背景

        Ciliary neurotrophic factor (CNTF) is a member of the cytokine family. It is a polypeptide hormone that have functions in promoting neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. Its actions appear to be restricted to the nervous system. Ciliary neurotrophic factor (CNTF) has biological effects through the activation of a multi-subunit receptor complex, consisting of an extracellular CNTF binding subunit(CNTFα) and two transmembrane signal transduction proteins: glycoprotein gp130 and LIF receptor. CNTF is considered as a potent survival factor of neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. CNTF is also a survival factor for neurons of the peripheral sensory sympathetic, and ciliary ganglia. It has been reported that CNTF could be an agent that has therapeutic potential and possibly induces differentiation of large multipolar ganglionic phenotype in a subset of progenitors.

        CNTFR 参考文献

        • Dutt K, et al. (2010) Ciliary neurotrophic factor: a survival and differentiation inducer in human retinal progenitors. In Vitro Cell Dev Biol Anim. 46 (7) : 635-46.
        • Lam A, et al. ( 1991) Sequence and structural organization of the human gene encoding ciliary neurotrophic factor. Gene 102 (2) : 271-6.
        • Bazan JF. ( 1991) Neuropoietic cytokines in the hematopoietic fold. Neuron 7 (2) : 197-208.

        Note: Flag® is a registered trademark of Sigma Aldrich Biotechnology LP. It is used here for informational purposes only.