Coronavirus Nucleocapsid Proteins, Antibodies, cDNA Clones, ELISA Kits Research Reagents

All Coronavirus Nucleocapsid reagents are produced in house and quality controlled, including 18 Coronavirus Nucleocapsid Antibody, 1 Coronavirus Nucleocapsid ELISA, 17 Coronavirus Nucleocapsid Gene, 11 Coronavirus Nucleocapsid IP Kit, 4 Coronavirus Nucleocapsid Lysate, 11 Coronavirus Nucleocapsid Protein. All Coronavirus Nucleocapsid reagents are ready to use.

All Coronavirus Nucleocapsid Reagents

Coronavirus Nucleocapsid Protein (11)

Coronavirus Nucleocapsid Antibody (18)

    Coronavirus Nucleocapsid ELISA 试剂盒(即用型)& ELISA 抗体对套装(非即用型)(1)

    Coronavirus Nucleocapsid cDNA Clone (17)

    2019-nCoV

    In expression vector

    SARS-CoV-2

    In lentiviral vector

    SARS-CoV,Strain Tor2

    In expression vector

    In lentiviral vector

    MERS-CoV

    In expression vector

    Coronavirus Nucleocapsid Lysate (4)

      Coronavirus Nucleocapsid 分子背景

      Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.

      Coronavirus Nucleocapsid 参考文献

        1. 1.Van Boheemen S, et al. (2012), MBio. 3(6):e00473-12.
        2. Bisht H. et al., 2004, Proc Natl Acad Sci. 101 (17): 6641-6.
        3. Li W. et al., 2005, Science. 309 (5742): 1864-8.

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