Carboxypeptidase B1 Proteins, Antibodies, cDNA Clones, ELISA Kits Research Reagents

All Carboxypeptidase B1 reagents are produced in house and quality controlled, including 13 Carboxypeptidase B1 Antibody, 3 Carboxypeptidase B1 ELISA, 41 Carboxypeptidase B1 Gene, 2 Carboxypeptidase B1 Lysate, 2 Carboxypeptidase B1 Protein, 2 Carboxypeptidase B1 qPCR. All Carboxypeptidase B1 reagents are ready to use.

Carboxypeptidase B1 Protein (2)

    Carboxypeptidase B1 Antibody (13)

      Carboxypeptidase B1 ELISA 试剂盒(即用型)& ELISA 抗体对套装(非即用型)(3)

      Carboxypeptidase B1 cDNA Clone (41)


      克隆载体 cDNA 产品

      In lentiviral vector


      克隆载体 cDNA 产品

      In lentiviral vector


      克隆载体 cDNA 产品

      In lentiviral vector

      Carboxypeptidase B1 Lysate (2)

        Carboxypeptidase B1 分子背景

        Carboxypeptidase B1, also well known as pancreatic procarboxypeptidase B (PCPB), is a highly pancreas -specific protein (PASP), and has been identified previously as a serum marker for acute pancreatitis and pancreatic graft rejection. As the prototype for those human exopeptidases that cleave off basic C-terminal residues, CPB1 specifically cleaves the C-terminal Arg and Lys residues with a preference for Arg. The B1 and B2 forms of procarboxypeptidase B differ from each other mainly in isoelectric point.The deduced amino acid sequence of PCPB predicts a 416-amino acid preproenzyme consisting of a 15-aa signal peptide, a 95-aa activation peptide and a 37-aa mature chain. The secreted PCPB zymogen is converted to enzymatically active CPB1 by limited proteolysis by trypsin.

        Carboxypeptidase B1 参考文献

        • Yamamoto, K.K. et al., 1992, J. Biol. Chem. 267: 2575-2581.
        • Pezzilli, R. et al., 1994, Digestion. 55: 73-77.
        • Barbosa Pereira, P.J. et al., 2002, J. Mol. Biol. 321: 537-547.

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