eIF5A Proteins, Antibodies, cDNA Clones Research Reagents

All eIF5A reagents are produced in house and quality controlled, including 1 eIF5A Antibody, 45 eIF5A Gene, 1 eIF5A Protein, 3 eIF5A qPCR. All eIF5A reagents are ready to use.

eIF5A Protein (1)

    eIF5A Antibody (1)

      eIF5A cDNA Clone (45)

      BC000751

      克隆载体 cDNA 产品

      In lentiviral vector

      NM_181582.4

      克隆载体 cDNA 产品

      In lentiviral vector

      NM_001033681.1

      克隆载体 cDNA 产品

      In lentiviral vector

      eIF5A 分子背景

      EIF-5A, also known as EIF5, functions in start site selection as a GTPase accelerating protein (GAP) for the eukaryotic translation initiation factor (eIF) 2•GTP•tRNA ternary complex within the ribosome-bound pre-initiation complex. In protein synthesis initiation, eIF2 functions in its GTP-bound state to deliver initiator methionyl-tRNA to the small ribosomal subunit and is necessary for protein synthesis in all cells. EIF-5A stabilizes the binding of GDP to eIF2 and is therefore a bi-functional protein that acts as a GDP dissociation inhibitor (GDI). EIF-5A also interacts with eIF1 and eIF3 and binds the eIF2-GTP/Met-tRNA ternary complex along with the 4S ribosome subunit.

      eIF5A 参考文献

      • Jenkins ZA. et al., 2001, Genomics. 71 (1): 101-9.
      • Guan XY. et al., 2001, Cancer Res. 61 (9): 3806-9.
      • Strausberg RL. et al., 2003, Proc Natl Acad Sci. 99 (26): 16899-903.
      • Clement PM. et al., 2003, Eur J Biochem. 270 (21): 4254-63.

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