Flow Cytometry (FACS) Antibody Biological Target


Flow cytometry is a method to evaluate cell membrane proteins and intracellular proteins as well as peptides and DNA. The principle behind FACS is an antigen-antibody reaction, with the antibodies being fluorescently labelled. There are three fluorescent proteins (R-PE, APC, and PerCP) conjugated to antibodies. Flow cytometry quantification is carried out with intercalating color labels (without the antibody). Flow cytometry antibodies are widely used in cell counting, cell sorting, biomarker detection andprotein engineering.
Biological target is very critical to drug discovery, drug development and disease diagnosis. Based on published estimates, there are approximately 1100 host biological targets and 200 pathogen biological targets. Biological target reagents can be used in pharmaceutical industry and academic biomedical research for immunomodulation, inflammation, cardiovascular diseases, central nervous system (CNS) and cancer etc.