GATA2 cDNA Clones Research Reagents

All GATA2 reagents are produced in house and quality controlled, including 15 GATA2 Gene, 1 GATA2 qPCR. All GATA2 reagents are ready to use.

GATA2 cDNA Clone (15)

NM_001145661.1

克隆载体 cDNA 产品

In lentiviral vector

GATA2 qPCR Primer (1)

GATA2 分子背景

GATA2 deficiency is a recently described genetic disorder affecting hematopoietic stem cells and is associated with immunodeficiency, hematologic malignancy, and various cutaneous pathologies including cutaneous tumors. GATA2 is a transcription factor that binds to the promoter of hematopoietic genes. By regulating bone trabecularization, GATA2 expression in the osteogenic lineage may contribute to the anatomical and cellular microenvironment of the HSC niche required for hematopoiesis. GATA2 deficiency presents with a spectrum of phenotypes including increased susceptibility to viral and bacterial infections, multi-lineage cytopenias, aplastic anemia, leukemic transformation and lymphedema.

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