GBA3 Proteins, Antibodies, cDNA Clones Research Reagents

All GBA3 reagents are produced in house and quality controlled, including 8 GBA3 Antibody, 15 GBA3 Gene, 1 GBA3 Lysate, 1 GBA3 Protein, 1 GBA3 qPCR. All GBA3 reagents are ready to use.

GBA3 Protein (1)

    GBA3 Antibody (8)

      GBA3 cDNA Clone (15)

      NM_020973.3

      克隆载体 cDNA 产品

      In lentiviral vector

      GBA3 qPCR Primer (1)

      GBA3 Lysate (1)

        GBA3 分子背景

        Cytosolic beta-glucosidase, also known as Cytosolic beta-glucosidase-like protein 1, GBA3, CBG and CBGL1 is a cytoplasm protein which belongs to theglycosyl hydrolase 1 family and Klotho subfamily. GBA3 / CBGL1 is a glycosidase probably involved in the intestinal absorption and metabolism of dietary flavonoid glycosides. GBA3 / CBGL1 is present in small intestine (at protein level). GBA3 / CBGL1 is expressed in liver, small intestine, colon, spleen and kidney. GBA3 / CBGL1 is down-regulated in renal cell carcinomas and hepatocellular carcinomas. GBA3 / CBGL1 is able to hydrolyze a broad variety of glycosides including phytoestrogens, flavonols, flavones, flavanones and cyanogens. GBA3 / CBGL1 possesses beta-glycosylceramidase activity and may be involved in a nonlysosomal catabolic pathway of glycosylceramide.

        GBA3 参考文献

        • Yahata K., et al.,(2000), Molecular cloning and expression of a novel klotho-related protein. J. Mol. Med. 78:389-394.
        • de Graaf M., et al., (2001), Cloning and characterization of human liver cytosolic beta-glycosidase.Biochem. J. 356:907-910.
        • Berrin J.-G., et al.,(2002), Functional expression of human liver cytosolic beta-glucosidase in Pichia pastoris. Insights into its role in the metabolism of dietary glucosides.Eur. J. Biochem. 269:249-258.

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