GGT1 Proteins, Antibodies, cDNA Clones Research Reagents

All GGT1 reagents are produced in house and quality controlled, including 5 GGT1 Antibody, 27 GGT1 Gene, 1 GGT1 Lysate, 1 GGT1 Protein, 2 GGT1 qPCR. All GGT1 reagents are ready to use.

GGT1 Protein (1)

    GGT1 Antibody (5)

      GGT1 cDNA Clone (27)


      In expression vector


      克隆载体 cDNA 产品

      In lentiviral vector


      克隆载体 cDNA 产品

      In lentiviral vector

      GGT1 qPCR Primer (2)

      GGT1 Lysate (1)

        GGT1 分子背景

        GGT1 belongs to the gamma-glutamyltransferase protein family. Many members of this family have not yet been fully characterized and some of which may represent pseudogenes. GGT1 is composed of a heavy chain and a light chain. It catalyzes the transfer of the glutamyl moiety of glutathione to a variety of amino acids and dipeptide acceptors. GGT1 also initiates extracellular glutathione (GSH) breakdown, provides cells with a local cysteine supply and contributes to maintain intracelular GSH level. As part of the cell antioxidant defense mechanism, GGT1 can be detected in fetal and adult kidney and liver, adult pancreas, stomach, intestine, placenta and lung. Defects in GGT1 can cause glutathionuria which is known as an autosomal recessive disease.

        GGT1 参考文献

        • Bulle F, et al. (1987) Assignment of the human gamma-glutamyl transferase gene to the long arm of chromosome 22. Hum Genet. 76(3):283-6.
        • Tate SS, et al. (1988) Renal gamma-glutamyl transpeptidases: structural and immunological studies. Arch Biochem Biophys. 262(2):397-408.
        • Tate SS, et al. (1988) In vitro translation and processing of human hepatoma cell (Hep G2) gamma-glutamyl transpeptidase. Biochem Biophys Res Commun. 154(3):1167-73.

        Note: Flag® is a registered trademark of Sigma Aldrich Biotechnology LP. It is used here for informational purposes only.