Immunohistochemical techniques is a methodology which based on antigen-antibody immunological response to its theoretical foundation. It plays an important role in basic and clinical medical research in the field of biology, especially in the diagnosis of diseases of the tumors, differential diagnosis and pathogenesis research provides a powerful tool. With the development of new technologies, hundreds of kinds of antibodies used in various areas of clinical research, the majority of these antibodies play an important supporting role in the diagnosis of difficult cases. It has important implications for the patient's prognosis and guide treatment.
Immunohistochemistry is the most important application is to distinguish between primary lung tumors and secondary tumors in the diagnosis of lung cancer. It can distinguish lung cancer from other cancers (colon, breast, prostate, pancreatic, stomach, kidney, bladder, ovary , uterine cancer, etc.). Immunohistochemistry also help distinguish small cell carcinoma and non-small cell carcinoma, there are many lung-specific markers such as surfactant proteins, TTF-1, and napsin A , etc.
Immunochemical staining of human FABP4 in human lung cancer with rabbit monoclonal antibody (0.5 µg/mL, formalin-fixed paraffin embedded sections).
Immunochemical staining of human PDRG1 in human lung cancer with rabbit polyclonal antibody (0.1 µg/mL, formalin-fixed paraffin embedded sections).
Immunochemical staining of human TNFAIP8 in human lung cancer with rabbit polyclonal antibody (0.5 µg/mL, formalin-fixed paraffin embedded sections).