Immunohistochemistry, using the basic principles of immunology - the antigen-antibody reaction, namely antigen and antibody specific binding principle, by chemical reaction of the labeled antibody reagent (luciferase, an enzyme, metal ions, isotopes) to confirm the antigens (peptides and proteins) in tissues, its location, qualitative and quantitative research, called immunohistochemistry (immunohistochemistry) or immunocytochemistry techniques (immunocytochemistry).It combined the specific of immune response with visibility of histochemistry by means of a microscope (including fluorescence microscopy, electron microscopy) imaging and amplification, detection of various antigens in a cell, subcellular level, such as proteins, polypeptides, enzymes, hormones, pathogens, and receptors. Immunohistochemical techniques have developed rapidly in recent years. It was limited to immunofluorescence techniques in 1950s, but gradually developed after the 1950s to establish a highly sensitive and more practical immunization enzyme technology.
The lungs are a pair of spongy, air-filled organs located on either side of the chest, Their function is to extract oxygen from the atmosphere and transfer it into the bloodstream, and to releasecarbon dioxide from the bloodstream into the atmosphere, a process of gas exchange in the respiratory system. Lung diseases are some of the most common medical conditions in the world. Smoking, infections, and genetics are responsible for most lung diseases. Lung cancer is a complex disease to treat and understand. What many people don't know is that lung cancer causes more deaths than the next three most common cancers combined (colon, breast and prostate). There are two different types of lung cancer - small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC) in. Non-small cell lung cancer is more common. Accounting for about 80 percent of lung cancer cases. Compared with small cell lung cancer, non-small cell lung cancer usually grows and spreads to other parts of the body slowly. There are three different types of non-small cell lung cancer: adenocarcinoma, squamous cell carcinoma, and large cell carcinoma. Each type is different, but they are grouped together because they are treated similarly. There are two different types of small cell lung cancer: small cell carcinoma (oat cell cancer) and the combined small cell carcinoma. The types of small cell lung cancer are named for the kinds of cells found in the cancer and how the cells look when viewed under a microscope. Many different antigens have been described and investigated in lung cancer. The most commonly used markers circulating in the blood are neuron specific enolase (NSE), carcinoembryonic antigen (CEA), cytokeratin 19 fragments (CYFRA 21-1), squamous cell carcinoma antigen (SCC), cancer antigen CA 125 (CA 125) and tissue polypeptide antigen (TPA.)
Different species of lung slices as follows: