Immunohistochemistry, using the basic principles of immunology - the antigen-antibody reaction, namely antigen and antibody specific binding principle, by chemical reaction of the labeled antibody reagent (luciferase, an enzyme, metal ions, isotopes) to confirm the antigens (peptides and proteins) in tissues, its location, qualitative and quantitative research, called immunohistochemistry (immunohistochemistry) or immunocytochemistry techniques (immunocytochemistry).It combined the specific of immune response with visibility of histochemistry by means of a microscope (including fluorescence microscopy, electron microscopy) imaging and amplification, detection of various antigens in a cell, subcellular level, such as proteins, polypeptides, enzymes, hormones, pathogens, and receptors. Immunohistochemical techniques have developed rapidly in recent years. It was limited to immunofluorescence techniques in 1950s, but gradually developed after the 1950s to establish a highly sensitive and more practical immunization enzyme technology.
The small intestine or small bowel is the part of the gastrointestinal tract between the stomach and thelarge intestine. The small intestine is a long-term, highly tortuous tube digestive system, absorbing about 90 percent of nutrients from the food we eat. The small intestine is made up of the duodenum, jejunum, and ileum. Together with the esophagus, large intestine, and the stomach, it forms the gastrointestinal tract. The small intestine has two important functions. The digestive process is completed in the small intestine by enzymes and other substances made by intestinal cells, the pancreas, and the liver. An enzyme secreted in the intestinal wall that breakdown starches and sugars. Pancreas secretes enzymes into the small intestine to help breakdown carbohydrates, fats and proteins. Liver produces bile, which is stored in the gallbladder. Bile helps fat molecules (otherwise it is insoluble in water) was dissolved, so they can be absorbed by the body. A variety of target molecules expressed on small intestine tissue is used for the clinical diagnosis of small intestine disease, small intestine tissue is commonly used in immunohistochemical detection. IHC is an important means to be widely used to detect small intestine disease.
Different species of small intestine slices as follows: