Immunohistochemistry (IHC) Antibody-Stem Cell

Background

Immunohistochemistry is the localization of antigens or proteins in tissue sections by the use of labeled antibodies as specific reagents through antigen-antibodyinteractions. Immunohistochemical antibody is widely used in the diagnosis of abnormal cells such as those found in cancerous tumors. Immunohistochemical antibody is also widely used in basic research to understand the distribution and localization of biomarkers and differentially expressed proteins in different parts of a biological tissue.

Stem Cells are characterised by their two properties of capability of renewing themselves and differentiating into a diverse range of cell types. The two broad types of mammalian stem cells are: embryonic stem cells and somatic or adult stem cells. Embryonic stem cells are isolated from the inner cell mass of blastocysts, while adult stem cells are found in adult tissues. In a developing embryo, stem cells can differentiate into all of the specialized embryonic tissues. In adult organisms, stem cells and progenitor cells act as a repair system for the body, dividing essentially without limit to replenish specialized cells. Because of their pluripotency and unlimited capacity for self-renewal, embryonic stem cell therapies have been proposed for regenerative medicine and tissue replacement after injury or disease. Reprogramming of somatic cells with defined factors can be a resolution to the problem of allogeneic stem cell transplantation in embryonic stem cell therapies. Adult cells, which have been genetically reprogrammed to an embryonic stem cell–like state by being forced to express genes and factors important for maintaining the defining properties of embryonic stem cells, are referred to as induced pluripotent stem cells (iPSCs). Stem cell related antibody is an important means in the study of stem cells, stem cell related antibody provides the effective and fast method for stem cell separation, stem cell purification and identification of stem cell marker. Stem cell related Growth Factors, Chemokines and Cytokines play an important role in the study of stem cells. The use of different stem cell related growth Factors, chemokines and cytokines in particular conditions on stem cells were induced toward a particular cell differentiation. Stem cell meidum is the foundation of stem cell related research and stem cell application.