Immunohistochemistry (IHC) Antibody-Uterus Tissue

Immunohistochemistry, using the basic principles of immunology - the antigen-antibody reaction, namely antigen and antibody specific binding principle, by chemical reaction of the labeled antibody reagent (luciferase, an enzyme, metal ions, isotopes) to confirm the antigens (peptides and proteins) in tissues, its location, qualitative and quantitative research, called immunohistochemistry (immunohistochemistry) or immunocytochemistry techniques (immunocytochemistry).It combined the specific of immune response with visibility of histochemistry by means of a microscope (including fluorescence microscopy, electron microscopy) imaging and amplification, detection of various antigens in a cell, subcellular level, such as proteins, polypeptides, enzymes, hormones, pathogens, and receptors. Immunohistochemical techniques have developed rapidly in recent years. It was limited to immunofluorescence techniques in 1950s, but gradually developed after the 1950s to establish a highly sensitive and more practical immunization enzyme technology.

The uterus also commonly known as the womb is a female reproductive organ located between the bladder and the rectum, in the pelvic area. The human uterus is pear-shaped and about 3 in. (7.6 cm) long, 4.5 cm broad (side to side) and 3.0 cm thick (anteroposterior). Uterine have three layers: an inner layer (endometrium); the middle muscular layer (myometrium); and an outer layer (perimetrium). The uterus is connected to the fallopian tubes, cervix, and (through the cervix) vagina. The uterus has several important functions in the body including a variety of reproductive function, such as implantation, pregnancy, labor, delivery and menstruation. In menstruating females the ovaries release eggs that travel via the fallopian tubes to the uterus. If fertilized, the eggs will bind themselves to the wall of the uterus and the fetus will develop. The uterus nourishes and protects the fetus until birth. A variety of target molecules expressed on uterus tissue is used for the clinical diagnosis of uterus disease, uterus tissue is commonly used in immunohistochemical detection. IHC is an important means to be widely used to detect uterus disease.

Different species of uterus slices as follows: