IL-6 Proteins, Antibodies, cDNA Clones, ELISA Kits Research Reagents
All IL-6 Reagents
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IL-6 Protein (6)Recombinant IL-6 proteins are expressed by E. coli with fusion tags as Native.
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IL-6 Antibody (26)IL-6 antibodies are validated with different applications, which are IHC-P, ELISA, WB, Neutralization, IP, ELISA(Cap), ELISA(Det).
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IL-6 ELISA Kit (2)IL-6 ELISA Kits are quality controlled by 8 internation QC standards which guarantee every ELISA Kit with high quality.
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IL-6 cDNA Clone (66)IL-6 cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each IL-6 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
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IL-6 qPCR Primer (3)Verified forward and reverse primers for analyzing the quantitative expression of gene. The primer mix has been verified to generate satisfactory qPCR data on Roche LightCycler480.
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IL-6 IP Kit (1)The Anti-IL-6 magnetic Beads, conjugated with Anti-IL-6 antibody, are used for immuneprecipitation (IP) of IL-6 proteins which expressed in vitro expression systems.
IL-6 Protein (6)
IL-6 Antibody (26)
IL-6 ELISA 试剂盒（即用型）& ELISA 抗体对套装（非即用型）(2)
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灵敏度: 1.24 pg/mL线性范围: 5.47-350
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线性范围: 9.38-600
IL-6 cDNA Clone (66)
克隆载体 cDNA 产品
In expression vector
In lentiviral vector
克隆载体 cDNA 产品
In expression vector
In lentiviral vector
克隆载体 cDNA 产品
In expression vector
In lentiviral vector
克隆载体 cDNA 产品
In expression vector
In lentiviral vector
克隆载体 cDNA 产品
In expression vector
In lentiviral vector
IL-6 qPCR Primer (3)
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Human IL-6 qPCR Primer Pair HP100427
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Mouse IL-6 qPCR Primer Pair MP200166
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Rat IL-6 qPCR Primer Pair RP300072
IL-6 IP Kit (1)
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IL-6 分子背景
Interleukin-6 (IL-6) is a multifunctional α-helical cytokine that regulates cell growth and differentiation of various tissues, which is known particularly for its role in the immune response and acute phase reactions. IL-6 protein is secreted by a variety of cell types including T cells and macrophages as phosphorylated and variably glycosylated molecule. It exerts actions through the its heterodimeric receptor composed of IL-6R that lacks the tyrosine/kinase domain and binds IL-6 with low affinity, and ubiquitously expressed glycoprotein 13 (gp13) that binds the IL-6. IL-6R complex with high affinity and thus transduces signals. IL-6 is also involved in hematopoiesis, bone metabolism, and cancer progression, and has been defined an essential role in directing transition from innate to acquired immunity.
IL-6 参考文献
- Heinrich PC. et al. (2003). Principles of interleukin-6-type cytokine signalling and its regulation. Biochem J. 374: 1-20.
- Rose-John S, et al. (2007) The IL-6/sIL-6R complex as a novel target for therapeutic approaches. Expert Opin Ther Targets. 11(5): 613-24.
- Dinh W, et al. (2009) Elevated plasma levels of TNF-alpha and interleukin-6 in patients with diastolic dysfunction and glucose metabolism disorders. Cardiovasc Diabetol. 8:58.
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