IL17RC Proteins, Antibodies, cDNA Clones Research Reagents

IL17RC (Interleukin 17 Receptor C, also known as CANDF9; IL17RL; IL17-RL), located on 3p25.3; 3p25.3-p24.1, is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, and frog. The gene produces an 86240 Da protein composed of 791 amino acids. This gene encodes a single-pass type I membrane protein that shares similarity with the interleukin-17 receptor (IL-17RA). Diseases such as Candidiasis, Familial, 9, and Chronic Mucocutaneous Candidiasis are associated with IL17RC. The related pathways of IL17RC include IL-17 Family Signaling Pathways and Akt Signaling.

IL17RC Protein (2)

    IL17RC Antibody (4)

      IL17RC cDNA Clone (2)

      NM_001203263.1

      In expression vector

      NM_134159.4

      克隆载体 cDNA 产品

      IL17RC Lysate (2)

        IL17RC 分子背景

        IL17RC (Interleukin 17 Receptor C) is a Protein Coding gene. This gene encodes a single-pass type I membrane protein that shares similarity with the interleukin-17 receptor (IL-17RA). IL17RC is widely expressed in the prostate, skin, and other tissues. The hypomethylation within the IL17RC gene promoter in peripheral blood is not suitable for use as a clinical biomarker of AMD. This study highlights the need for considerable replication of epigenetic association studies before clinical application. methylation of IL17RC could play as a marker in choroidal neovascularization (CNV) and degeneration of retinal pigment epithelium (RPE) cells in vitro. Diseases associated with IL17RC include Candidiasis, Familial, 9, and Chronic Mucocutaneous Candidiasis.

        IL17RC 参考文献

        • Allen W, et al. (2010) IL-17RC: A partner in IL-17 signaling and beyond. Semin Immunopathol. 32(1): 33-42.
        • You ZB, et al. (2007) Differential Expression of IL-17RC Isoforms in Androgen-Dependent and Androgen-Independent Prostate Cancers1. Neoplasia. 9(6): 464-70.
        • Zrioual S, et al. (2008) IL-17RA and IL-17RC receptors are essential for IL-17A-induced ELR+ CXC chemokine expression in synoviocytes and are overexpressed in rheumatoid blood. J Immunol. 180(1): 655-63.
        • Kuestner RE, et al. (2010) Identification of the IL-17 Receptor Related Molecule IL-17RC as the Receptor for IL-17F. J Immunol.179(8): 5462-73.

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