IL9R Proteins, Antibodies, cDNA Clones Research Reagents

IL9R (Interleukin 9 Receptor, also known as CD129; IL-9R), located on Xq28 and Yq12, is conserved in Rhesus monkey, dog, cow, mouse, rat, and chicken. The gene produces a 57147 Da protein composed of 521 amino acids. The protein encoded by this gene is a cytokine receptor that specifically mediates the biological effects of interleukin 9 (IL9). Diseases such as Asthma and Bronchitis are associated with IL9R. The related pathways of IL9R include Common Cytokine Receptor Gamma-Chain Family Signaling Pathways and AKT Signaling Pathway.

IL9R Protein (1)

    IL9R Antibody (4)

      IL9R cDNA Clone (28)

      BC051337

      In expression vector

      In lentiviral vector

      NM_017021.1

      克隆载体 cDNA 产品

      In lentiviral vector

      XM_001100521.2

      克隆载体 cDNA 产品

      In lentiviral vector

      IL9R qPCR Primer (2)

      IL9R Lysate (1)

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        IL9R 分子背景

        IL9R (Interleukin 9 Receptor) is a Protein Coding gene. The protein encoded by this gene is a cytokine receptor that specifically mediates the biological effects of interleukin 9 (IL9). IL9 is involved in mast cell maturation and the enhancement of IgE production by B cells. Furthermore, linkage data in the human and mice have suggested that IL9 may contribute to asthma. The ligand binding of this receptor leads to the activation of various JAK kinases and STAT proteins, which connect to different biologic responses. IL9R is known to be autosomal in mice and is X-linked only in primates. The more recent X linkage and more telomeric position of the IL9R gene may explain its autosomal, 'un-inactivated' transcriptional status.

        IL9R 参考文献

        • Demoulin JB. et al. (1998) Interleukin 9 and its receptor: an overview of structure and function. Int Rev Immunol. 16 (3-4): 345-64.
        • Sliva D. et al. (1999) Tip60 interacts with human interleukin-9 receptor alpha-chain. Biochem Biophys Res Commun. 263 (1): 149-55.
        • Renauld JC. et al. (1995) Interleukin-9 and its receptor: involvement in mast cell differentiation and T cell oncogenesis. J Leukoc Biol. 57 (3): 353-60.

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