Integrin beta 1 Proteins, Antibodies, cDNA Clones Research Reagents

ITGB1 (Integrin Subunit Beta 1, also known as CD29; FNRB; MDF2; VLAB; GPIIA; MSK12; VLA-BETA), located on 10p11.22, is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, C.elegans, and frog. The gene produces an 88415 Da protein composed of 798 amino acids. Integrins are heterodimeric proteins made up of alpha and beta subunits. Diseases such as Gallbladder Cancer and Breast Cancer are associated with ITGB1. The related pathways of ITGB1 include Integrin Pathway and Signaling by GPCR.

Integrin beta 1 Protein (1)

    Integrin beta 1 Antibody (11)

      Integrin beta 1 cDNA Clone (55)

      NM_002211.3

      克隆载体 cDNA 产品

      In lentiviral vector

      NM_010578.1

      克隆载体 cDNA 产品

      In lentiviral vector

      NM_017022.2

      克隆载体 cDNA 产品

      In lentiviral vector

      XM_005616949.2

      克隆载体 cDNA 产品

      XM_002805609.1

      克隆载体 cDNA 产品

      In lentiviral vector

      Integrin beta 1 Lysate (1)

        Integrin beta 1 分子背景

        ITGB1 (Integrin Subunit Beta 1) is a Protein Coding gene. This gene encodes a beta subunit, which is a type 1 transmembrane protein of the integrin beta chain family. ITGB1 is a heterodimeric cell-surface receptor involved in cell functions such as proliferation, migration, invasion, and survival. ITGB1 has been recognized to play a major role in tumor growth, invasion, and metastasis. Using luciferase assays, the researcher identified ITGB1 as a direct target of miR-134. ITGB1 is a direct target of miR-493-5p suggesting that ITGB1 and miR-493-5p may have potential prognostic value and may be useful as tumor biomarkers for the diagnosis of NSCLC patients. Diseases associated with ITGB1 include Gallbladder Cancer and Breast Cancer.

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