JAM-A/Junctional Adhesion Molecule A Proteins, Antibodies, cDNA Clones, ELISA Kits Research Reagents

All JAM-A/Junctional Adhesion Molecule A reagents are produced in house and quality controlled, including 11 JAM-A/Junctional Adhesion Molecule A Antibody, 2 JAM-A/Junctional Adhesion Molecule A ELISA, 39 JAM-A/Junctional Adhesion Molecule A Gene, 1 JAM-A/Junctional Adhesion Molecule A IP Kit, 5 JAM-A/Junctional Adhesion Molecule A Lysate, 5 JAM-A/Junctional Adhesion Molecule A Protein, 3 JAM-A/Junctional Adhesion Molecule A qPCR. All JAM-A/Junctional Adhesion Molecule A reagents are ready to use.

All JAM-A/Junctional Adhesion Molecule A Reagents

JAM-A/Junctional Adhesion Molecule A Protein (5)

    JAM-A/Junctional Adhesion Molecule A Antibody (11)

      JAM-A/Junctional Adhesion Molecule A ELISA 试剂盒(即用型)& ELISA 抗体对套装(非即用型)(2)

      JAM-A/Junctional Adhesion Molecule A cDNA Clone (39)

      NM_016946.4

      克隆载体 cDNA 产品

      In lentiviral vector

      NM_172647.2

      克隆载体 cDNA 产品

      In lentiviral vector

      NM_053796.1

      克隆载体 cDNA 产品

      In lentiviral vector

      JAM-A/Junctional Adhesion Molecule A IP Kit (1)

      JAM-A/Junctional Adhesion Molecule A Lysate (5)

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        JAM-A/Junctional Adhesion Molecule A 分子背景

        Junctional adhesion molecule-A (JAM-A), also known as F11 receptor (F11R) or Cluster of Differentiation 321 (CD321), is a transmembrane protein expressed at tight junctions of epithelial and endothelial cells, as well as on circulating leukocytes. JAM-A protein serves as a serotype-independent receptor for mammalian orthoreoviruses (reoviruses). It is also a ligand for the integrin LFA1, involves in leukocyte transmigration. As a cell adhesion molecule of the immunoglobulin superfamily, JAM-A protein involves in platelet adhesion, secretion and aggregation, and plays a crucial role in inflammatory thrombosis and atherosclerosis. In addition, it may be a potential therapeutic target for breast cancer.

        JAM-A/Junctional Adhesion Molecule A 参考文献

        • Guglielmi KM, et al. (2007) Reovirus binding determinants in junctional adhesion molecule-A. J Biol Chem. 282(24): 17930-40.
        • Yeung D, et al. (2008) Decreased junctional adhesion molecule-A expression during blood-brain barrier breakdown. Acta Neuropathol. 115(6): 635-42.
        • Ong KL, et al. (2009) Elevated plasma level of soluble F11 receptor/junctional adhesion molecule-A (F11R/JAM-A) in hypertension. Am J Hypertens. 22(5): 500-5.

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