Kallikrein 11 Proteins, Antibodies, cDNA Clones, ELISA Kits Research Reagents

KLK11 (Kallikrein Related Peptidase 11, also known as TLSP; PRSS20), located on 19q13.41, is a Protein Coding gene. The gene produces a 31059 Da protein composed of 282 amino acids. KLK11 belongs to the kallikrein subfamily of serine proteases, which are involved in a variety of enzymatic processes. KLK11 shares 48% amino acid sequence identity with mouse neuropsin. Diseases such as Thyroid Hormone Resistance, Selective Pituitary, and Prostate Cancer are associated with KLK11. The related pathways of KLK11 include Collagen chain trimerization and MSP-RON Signaling.

Kallikrein 11 Protein (2)

    Kallikrein 11 Antibody (6)

      Kallikrein 11 ELISA 试剂盒(即用型)& ELISA 抗体对套装(非即用型)(2)

      Kallikrein 11 cDNA Clone (26)

      NM_006853.2

      克隆载体 cDNA 产品

      In lentiviral vector

      NM_001177373.1

      克隆载体 cDNA 产品

      In lentiviral vector

      Kallikrein 11 Lysate (2)

        Kallikrein 11 分子背景

        kallikrein-related peptidase 11 (KLK11), also known as hippostasin, trypsin-like serine protease, and PRSS2, is a member of the human tissue kallikrein family. It is a subgroup of serine proteases with diverse physiological functions, which are implicated in carcinogenesis and some with potential that serving as novel biomarkers for ovarian and prostate cancer and other diseases. The KLK11 gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Two alternatively spliced forms exist, resulting in 25 (isoform 1) and 282 (isoform 2) amino acid sequences. Isoform 2 is identical to isoform 1, except for an inserted 32 amino acid segment. Isoform 1 is predominantly expressed in the brain whereas isoform 2 is preferentially expressed in the prostate.

        Kallikrein 11 参考文献

        • Yoshida S., et al.,(1998), cDNA cloning and expression of a novel serine protease, TLSP. Biochim. Biophys. Acta 1399:225-228.
        • Mitsui S., et al., (2000), A novel isoform of a kallikrein-like protease, TLSP/hippostasin, (PRSS20), is expressed in the human brain and prostate.Biochem. Biophys. Res. Commun. 272:205-211.
        • Yousef G.M., et al.,(2000), Genomic organization, mapping, tissue expression, and hormonal regulation of trypsin-like serine protease (TLSP PRSS20), a new member of the human kallikrein gene family.Genomics 63:88-96.

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