LILRA2 Proteins, cDNA Clones Research Reagents

LILRA2 (Leukocyte Immunoglobulin Like Receptor A2, also known as ILT1; LIR7; CD85H; LIR-7), located on 19q13.42, is a Protein Coding gene. The gene produces a 52992 Da protein composed of 483 amino acids. This gene encodes a member of a family of immunoreceptors that are expressed predominantly on monocytes and B cells, and at lower levels on dendritic cells and natural killer cells. Diseases such as Tuberculoid Leprosy and Leprosy 3 are associated with LILRA2. The related pathways of LILRA2 include Innate Immune System and Class I MHC mediated antigen processing and presentation.

LILRA2 Protein (2)

    LILRA2 cDNA Clone (14)

    BC017412

    克隆载体 cDNA 产品

    In lentiviral vector

    NM_001130917.3

    In expression vector

    LILRA2 qPCR Primer (1)

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    LILRA2 分子背景

    LILRA2 (Leukocyte Immunoglobulin Like Receptor A2, also known as LIR7 and ILT1) is a Protein Coding gene. The encoded protein is an activating receptor that inhibits dendritic cell differentiation and antigen presentation and suppresses the innate immune response. It is an activating receptor highly expressed in inflammatory tissues and is involved in granulocyte and macrophage activation. LILRA2 is primarily expressed on the surface of cells of the innate immunity including monocytes, macrophages, neutrophils, basophils, and eosinophils but not on lymphocytes and NK cells. LILRA2 cross-linking on monocytes induces pro-inflammatory cytokines while inhibiting dendritic cell differentiation and antigen presentation. Diseases associated with LILRA2 include Tuberculoid Leprosy and Leprosy 3.

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