MMP26 Proteins, Antibodies, cDNA Clones Research Reagents

MMP26 (Matrix Metallopeptidase 26), located on 11p15.4, is a Protein Coding gene. The gene produces a 29708 Da protein composed of 261 amino acids. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Diseases such as Endometrial Hyperplasia and Pyoderma Gangrenosum are associated with MMP26. The related pathways of MMP26 include Integrin Pathway and Matrix Metalloproteinases.

MMP26 Protein (1)

    MMP26 Antibody (1)

      MMP26 cDNA Clone (13)

      NM_021801.3

      克隆载体 cDNA 产品

      In lentiviral vector

      MMP26 qPCR Primer (1)

      MMP26 分子背景

      MMP26 (Matrix Metallopeptidase 26) is a Protein Coding gene. MMP26 is a member of matrix metalloproteinases (MMPs) and has been reported to be highly expressed in many cancers. The protein differs from most MMP family members in that it lacks a conserved C-terminal protein domain. It may hydrolyze collagen type IV, fibronectin, fibrinogen, beta-casein, type I gelatin, and alpha-1 proteinase inhibitor, and is also able to activate progelatinase B. MMP26 is a target gene of miR-125b, and the expression profile of MMP26 showed an inverse relationship with miR-125b in vivo and in vitro. The overexpression of MMP26 in SW1353 cells increased cell invasiveness, while inhibition of MMP26 decreased cell invasiveness.

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