MOB4 (MOB Family Member 4, Phocein) is a Protein Coding gene. The MOB4 gene, located on 2q33.1, is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, and rat, etc. MOB4 belongs to the MOB1/phocein family. 3 alternatively spliced human isoforms have been reported. This gene was identified based on its similarity with the mouse counterpart. Studies of the mouse counterpart suggest that the expression of this gene may be regulated during oocyte maturation and preimplantation following zygotic gene activation. MOB4 may also play a role in membrane trafficking, specifically in membrane budding reactions. MOB4 is widely expressed in the adrenal, esophagus, and other tissues. Diseases associated with MOB4 include Cerebral Cavernous Malformations 3 and Febrile Seizures, Familial, 6.