Peroxiredoxin 2 Proteins, Antibodies, cDNA Clones Research Reagents

All Peroxiredoxin 2 reagents are produced in house and quality controlled, including 2 Peroxiredoxin 2 Antibody, 75 Peroxiredoxin 2 Gene, 1 Peroxiredoxin 2 IP Kit, 2 Peroxiredoxin 2 Lysate, 2 Peroxiredoxin 2 Protein, 3 Peroxiredoxin 2 qPCR. All Peroxiredoxin 2 reagents are ready to use.

Peroxiredoxin 2 Protein (2)

    Peroxiredoxin 2 Antibody (2)

      Peroxiredoxin 2 cDNA Clone (75)

      NM_005809.4

      克隆载体 cDNA 产品

      In lentiviral vector

      NM_011563.5

      克隆载体 cDNA 产品

      In lentiviral vector

      BC058481.1

      克隆载体 cDNA 产品

      In lentiviral vector

      XM_004824207.1

      克隆载体 cDNA 产品

      In lentiviral vector

      XM_003639723.2

      克隆载体 cDNA 产品

      In lentiviral vector

      Peroxiredoxin 2 Lysate (2)

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        Peroxiredoxin 2 分子背景

        Peroxiredoxin-2, also known as Natural killer cell-enhancing factor B, NKEF-B, Thiol-specific antioxidant protein, Thioredoxin peroxidase 1, Thioredoxin-dependent peroxide reductase 1, PRDX2 and NKEFB, is a cytoplasm protein which belongs to theahpC / TSA family. Peroxiredoxin-2 / PRDX2 contains onethioredoxin domain. Peroxiredoxin-2 / PRDX2 is involved in redox regulation of the cell. It reduces peroxides with reducing equivalents provided through the thioredoxin system. Peroxiredoxin-2 / PRDX2 is not able to receive electrons from glutaredoxin. It may play an important role in eliminating peroxides generated during metabolism. Peroxiredoxin-2 / PRDX2 might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H2O2. The Peroxiredoxins / Prx are a family of peroxidases that can reduce H2O2 using an electron from thioredoxin (Trx) or other substances. The mammalian Peroxiredoxins / Prx family is divided into six groups ( PRDX1,PRDX2, PRDX3, PRDX4, PRDX5, PRDX6 ) on the basis of homology of amino acid sequences. They are located in the cytosol and play a role in the cell signaling system. All six mammalian peroxiredoxins are expressed in the lung. Peroxiredoxins / Prx is overexpressed in breast cancer tissues to a great extent suggesting that Peroxiredoxins / Prx has a proliferative effect and may be related to cancer development or progression.

        Peroxiredoxin 2 参考文献

        • Cha M.-K., et al., 1995,  Biochem. Biophys. Res. Commun. 217:900-7.
        • Noh,D.Y. et al., 2001, Anticancer Res. 21 (3B): 2085-90.
        • Chevallet M., et al., 2003, J. Biol. Chem. 278:37146-53.
        • Schremmer,B. et al., 2007, Subcell Biochem. 44 :317-44.
        • Gauci S., et al., 2009, Anal. Chem. 81:4493-501.

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