PRSS2 Proteins, Antibodies, cDNA Clones Research Reagents

PRSS2 (Serine Protease 2) is a protein coding gene located on human chromosome 7q34. PRSS2 is also known as TRY2, TRY8 and TRYP2. The human PRSS2 gene encodes a 26488 Da protein containing 247 amino acids. Among its related pathways are Collagen chain trimerization and Degradation of the extracellular matrix. PRSS2 is related to calcium ion binding and serine-type endopeptidase activity. PRSS1 is an important paralog of PRSS2 gene. PRSS2 is associated with some diseases, including Pancreatitis, Hereditary and Pancreatitis.

PRSS2 Protein (1)

    PRSS2 Antibody (1)

      PRSS2 cDNA Clone (40)


      克隆载体 cDNA 产品

      In lentiviral vector


      克隆载体 cDNA 产品

      In lentiviral vector


      克隆载体 cDNA 产品

      In lentiviral vector

      PRSS2 qPCR Primer (1)

      PRSS2 Lysate (1)

        PRSS2 分子背景

        Trypsin-2, also known as Trypsin II, Anionic trypsinogen, Serine protease 2, PRSS2 and TRY2, is a secreted protein that belongs to the trypsin serine protease family including Trypsin, PRSS1, PRSS2 and PRSS3. It consists of a signal peptide (residues 1-15), a pro region (residues 16-23), and a proteolytically active mature chain (residues 24-247). PRSS2 contains one peptidase S1 domain. It is secreted into the duodenum, hydrolysing peptides into their smaller building blocks, which is necessary for the uptake of protein in the food. It is secreted by the pancreas in the form of inactive zymogen, trypsinogen and cleaved to its active form in the small intestine when the pancreas is stimulated by cholecystokinin through the common activation mechanism.

        PRSS2 参考文献

        • Rawlings, N.D. et al.,1994, Meth. Enzymol. 244: 19–61.
        • Noone, P.G. et al., 2001, Gastroenterology. 121 (6): 1310-9.
        • Leiros, H.K. et al., 2004, Protein Sci. 13 (4): 1056–70.
        • Rónai,Z. et al., 2009, Biochem J. 418 (1):155-61.

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