SNAIL/SNAI1 Antibodies, cDNA Clones Research Reagents

SNAI1 (Snail Family Transcriptional Repressor 1) is a protein coding gene located on human chromosome 20q13.13. SNAI1 is also known as SNA, SNAH, SNAIL, SLUGH2, SNAIL1 and dJ710H13.1. The human SNAI1 gene encodes a 29083 Da protein containing 264 amino acids. The SNAI1 protein is broadly expressed in gall bladder, thyroid and other tissues. Among its related pathways are Development HGF signaling pathway and Neural Crest Differentiation. SNAI1 is related to sequence-specific DNA binding and proximal promoter DNA-binding transcription repressor activity, RNA polymerase II-specific. SNAI2 is an important paralog of SNAI1 gene. SNAI1 is associated with some diseases, including Gastroesophageal Junction Adenocarcinoma and Cercarial Dermatitis.

SNAIL/SNAI1 Antibody (1)

    SNAIL/SNAI1 cDNA Clone (15)

    NM_005985.3

    克隆载体 cDNA 产品

    In lentiviral vector

    SNAIL/SNAI1 分子背景

    The Snail family transcriptional repressor 1 (SNAI1) is known to promote metastatic phenotypes in renal cell carcinoma (RCC). Targeting the miR-211-5p/SNAI1 signaling pathway may be a novel therapeutic approach for the treatment of RCC metastasis. Given its central role in EMT and tumor metastasis, the cell has evolved multiple levels of regulatory mechanism at transcriptional, post-transcriptional, and post-translational level to regulate SNAI1 expression. SNAI1, a zinc-finger transcription factor, plays an important role in the induction of epithelial-mesenchymal transition (EMT) in various cancers.

    Note: Flag® is a registered trademark of Sigma Aldrich Biotechnology LP. It is used here for informational purposes only.