SOX2 Antibodies, cDNA Clones Research Reagents

All SOX2 reagents are produced in house and quality controlled, including 5 SOX2 Antibody, 1 SOX2 Gene, 2 SOX2 IP Kit. All SOX2 reagents are ready to use.

SOX2 Antibody (5)

    SOX2 cDNA Clone (1)

    NM_011443.4

    In expression vector

    SOX2 分子背景

    SOX2, also known as ANOP3, is a transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP26. SOX2 is critical for early embryogenesis and for embryonic stem cell pluripotency. It keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation. Defects in SOX2 can cause microphthalmia, syndromic, 3. A disease characterized by the rare association of malformations including uni- or bilateral anophthalmia or microphthalmia, and esophageal atresia with trachoesophageal fistula.

    SOX2 参考文献

    • Lu Y, et al., 2010, PLoS ONE. 5(6): e11022.
    • Gontan C, et al., 2008, Dev. Biol. 317 (1): 296-309.
    • Shi W, et al., 2006, J. Biol. Chem. 281 (33): 23319-25.

    Note: Flag® is a registered trademark of Sigma Aldrich Biotechnology LP. It is used here for informational purposes only.