SP-10/ACRV1 Proteins, Antibodies, ELISA Kits Research Reagents

All SP-10/ACRV1 reagents are produced in house and quality controlled, including 5 SP-10/ACRV1 Antibody, 1 SP-10/ACRV1 ELISA, 1 SP-10/ACRV1 Lysate, 1 SP-10/ACRV1 Protein. All SP-10/ACRV1 reagents are ready to use.

SP-10/ACRV1 Protein (1)

    SP-10/ACRV1 Antibody (5)

      SP-10/ACRV1 ELISA 试剂盒(即用型)& ELISA 抗体对套装(非即用型)(1)

      SP-10/ACRV1 Lysate (1)

        SP-10/ACRV1 分子背景

        Acrosomal protein SP-1, also known as Acrosomal vesicle protein 1 and ACRV1, is a testis-specific, differentiation antigen, that arises within the acrosomal vesicle during spermatogenesis, and is associated with the acrosomal membranes and matrix of mature sperm. Regulation of cell type-specific gene transcription is central to cellular differentiation and development. During spermatogenesis, a number of testis-specific genes are expressed in a precise spatiotemporal order. The longest transcript of ACRV1 / SP-1 is the most abundant, comprising 53-72% of the total acrosomal vesicle protein 1 messages; the second largest transcript comprises 15-32%; the third and the fourth largest transcripts account for 3.4-8.3% and 8.7-12.5%, respectively; and the remaining transcripts combined account for < 1% of the total acrosomal vesicle protein 1 message. ACRV1 / SP-1 is a testis-specific acrosomal protein that has been detected in several species including humans. It may be involved in sperm-zona binding or penetration, and it is a potential contraceptive vaccine immunogen for humans. ACRV1 / SP-1 may be involved in sperm-zona binding or penetration. It is also a intra-acrosomal protein that is considered to be a vaccine candidate for immunocontraception.

        SP-10/ACRV1 参考文献

        • Wright RM, et al.,1990, Biol Reprod. 42 (4): 693-701.
        • Kurth,B.E. et al., 1993, Anat Rec. 236 (4):619-25.
        • Golden WL, et al.,1994, Genomics.18 (2): 446-9. 
        • Foster,J.A. et al., 1994, Biol Reprod. 51 (6):1222-31.
        • Abhyankar,M.M. et al., 2007, J Biol Chem. 282 (50): 36143-54.

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