CD5L (蛋白 | 抗体 | cDNA 克隆 | ELISA 试剂盒)

All CD5L reagents are produced in house and quality controlled, including 7 CD5L Antibody, 2 CD5L ELISA, 26 CD5L Gene, 2 CD5L Lysate, 2 CD5L Protein, 2 CD5L qPCR. All CD5L reagents are ready to use.

CD5L Protein (2)

    CD5L Antibody (7)

      CD5L ELISA 试剂盒(即用型)& ELISA 抗体对套装(非即用型)(2)

      CD5L cDNA Clone (26)

      NM_005894.2

      克隆载体 cDNA 产品

      In lentiviral vector

      NM_009690.2

      克隆载体 cDNA 产品

      In lentiviral vector

      CD5L Lysate (2)

        CD5L 分子背景

        CD5L, also known as CD5 antigen-like, is a soluble protein belonging to group B of the scavenger receptor cysteine-rich (SRCR) superfamily and contains three SRCR domains. It is a secreted glycoprotein and expressed by macrophages presentin lymphoid tissues (spleen, lymph node, thymus, and bone marrow). It binds to myelomonocytic and lymphoid cells and may play an important role in the regulation of the innate and adaptive immune systems. CD5L functions as a pattern recognition molecule by binding both lipoteichoic acid (LTA) on Gram positive and lipopolysaccharide (LPS) on Gram negative bacteria. and the SRCR domain 1 of CD5L retains both the LPS and LTA binding activities. In addtion, it is revealed that CD5L seems to play a role as an inhibitor of apoptosis.

        CD5L 参考文献

        • Resnick, D. et al., 1994, Trends Biochem. Sci. 19: 5-8.
        • Gebe, J. A. et al., 1997, J. Biol. Chem. 272 (10): 6151–6158.
        • Sarrias, M.R. et al., 2004, Crit. Rev. Immunol. 24: 1-37.
        • Mukhopadhyay, S. and Gordon, S., 2004, Immunobiology 209: 39-49.
        • Sarrias, M. R. et al.,2005, J. Biol. Chem. 280 (42): 35391–35398.