ATP1B3 cDNA ORF Clone in Cloning Vector, Human

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ATP1B3 cDNA ORF Clone in Cloning Vector, Human: 产品信息

基因
种属
Human
NCBI 参考序列号
基因长度
840 bp
序列特征
Identical with the Gene Bank Ref. ID sequence.
产品特征
Full length Clone DNA of Human ATPase Na+/K+ transporting subunit beta 3
质粒
载体
测序引物
M13-47 and RV-M
质控
The plasmid is confirmed by full-length sequencing.
筛选
细菌筛选抗性
Ampicillin
储存 & 运输
运输方式
Each tube contains lyophilized plasmid.
储存条件
The lyophilized plasmid can be stored at ambient temperature for three months.

ATP1B3 cDNA ORF 核苷酸序列及氨基酸序列信息

**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**

关于 ATP1B3的更多信息

Entrez Gene ID

ATP1B3 cDNA ORF Clone in Cloning Vector, Human: 别称

ATPB-3 cDNA ORF Clone, Human; CD298 cDNA ORF Clone, Human

ATP1B3 背景信息

Enterovirus 71 (EV71) infection can cause severe diseases, and is becoming increasingly common in children. Human beta3 subunit of Na(+)/K(+)-ATPase (ATP1B3) protein was demonstrated to interact with the 3A protein of EV71. Although 3A protein had no effect on the expression of ATP1B3, EV71 infection resulted in elevated expression of ATP1B3 in RD cell line, both on messenger RNA (mRNA) and protein levels. And knockdown of ATP1B3 could significantly increase the replication of EV71, whereas overexpression of ATP1B3 significantly suppressed the replication of EV71 in RD cells. That the expression of ATP1B3 could induce the production of type-I interferons. ATP1B3 inhibit EV71 replication by enhancing the production of type-I interferons, which could act as a potential therapeutic target in EV71 infection.
全称
ATPase, Na+/K+ transporting, beta 3 polypeptide
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