Beclin 1/BECN1 cDNA ORF Clone in Cloning Vector, Human

Price:
Size:
Number:

Beclin 1/BECN1 cDNA ORF Clone in Cloning Vector, Human: 产品信息

基因
种属
Human
NCBI 参考序列号
基因长度
1353 bp
序列特征
Identical with the Gene Bank Ref. ID sequence.
产品特征
Full length Clone DNA of Human beclin 1
质粒
载体
测序引物
M13-47 and RV-M
质控
The plasmid is confirmed by full-length sequencing.
筛选
细菌筛选抗性
Ampicillin
储存 & 运输
运输方式
Each tube contains lyophilized plasmid.
储存条件
The lyophilized plasmid can be stored at ambient temperature for three months.

Beclin 1/BECN1 cDNA ORF 核苷酸序列及氨基酸序列信息

**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**

Beclin 1/BECN1 cDNA ORF Clone in Cloning Vector, Human: 别称

ATG6 cDNA ORF Clone, Human; beclin1 cDNA ORF Clone, Human; VPS30 cDNA ORF Clone, Human

Beclin 1/BECN1 背景信息

BECN1 (Beclin 1), a highly conserved eukaryotic protein, is a key regulator of autophagy, a cellular homeostasis pathway, and also participates in vacuolar protein sorting, endocytic trafficking, and apoptosis. BECN1 is important for embryonic development, the innate immune response, tumor suppression, and protection against neurodegenerative disorders, diabetes, and heart disease. BECN1 mediates autophagy as a core component of the class III phosphatidylinositol 3-kinase complexes.The decreased mRNA expression of the autophagy gene BECN1 may contribute to the pathogenesis and progression of HER2-enriched, basal-like, and TP53 mutant breast cancers. BECN1/Beclin 1 is regarded as a critical component in the class III phosphatidylinositol 3-kinase (PtdIns3K) complex to trigger autophagy in mammalian cells. Despite its significant role in a number of cellular and physiological processes, the exact function of BECN1 in autophagy remains controversial.
全称
beclin 1, autophagy related
研究领域
Related Pathways
  • Autophagy Pathway
    Autophagy Pathway

Beclin 1/BECN1 cDNA ORF Clone, Rat, 相关产品

添加购物车成功! 添加购物车失败!请再次尝试 正在更新购物车,请稍后 U.S.A.