c-Myc/MYC cDNA ORF Clone, Human, N-His tag

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c-Myc/MYC cDNA ORF Clone, Human, N-His tag: 产品信息

基因
种属
Human
NCBI 参考序列号
基因长度
1365 bp
序列特征
Identical with the Gene Bank Ref. ID sequence.
产品特征
Full length Clone DNA of Human v-myc myelocytomatosis viral oncogene homolog (avian) with N terminal His tag.
质粒
启动子
Enhanced CMV promoter
载体
限制性酶切位点
KpnI + XbaI (6kb + 1.42kb)
标签序列
His Tag Sequence: CACCATCACCACCATCATCACCACCATCAC
测序引物
T7( 5' TAATACGACTCACTATAGGG 3' )
BGH( 5' TAGAAGGCACAGTCGAGG 3' )
质控
The plasmid is confirmed by full-length sequencing.
筛选
细菌筛选抗性
Kanamycin
细胞筛选抗性
Hygromycin
应用
Stable or Transient mammalian expression
储存 & 运输
运输方式
Each tube contains lyophilized plasmid.
储存条件
The lyophilized plasmid can be stored at ambient temperature for three months.

c-Myc/MYC cDNA ORF 核苷酸序列及氨基酸序列信息

**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**

c-Myc/MYC cDNA ORF Clone, Human, N-His tag: 验证图片

c-Myc/MYC cDNA ORF Clone, Human, N-His tag: 别称

bHLHe39 cDNA ORF Clone, Human; c-Myc cDNA ORF Clone, Human; MRTL cDNA ORF Clone, Human; MYCC cDNA ORF Clone, Human

c-Myc/MYC 背景信息

MYC (MYC Proto-Oncogene, BHLH Transcription Factor) is a Protein Coding gene. This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis, and cellular transformation. MYC largely functions as a transcription factor that promotes the expression of numerous target genes to coordinate death, proliferation, and metabolism at the cellular, tissue, and organismal levels. MYC is one of the most important oncogenes in cancer. MYC overexpression can be achieved through a variety of mechanisms, including gene duplications, chromosomal translocations, or somatic mutations leading to increased MYC stability. It is widely expressed in the gall bladder, esophagus, and other tissues. Diseases associated with MYC include Burkitt Lymphoma and High-Grade B-Cell Lymphoma With Myc And/ Or Bcl2 And/Or Bcl6 Rearrangement.
全称
v-myc avian myelocytomatosis viral oncogene homolog
Related Pathways
  • EGFR Signaling Pathway
    EGFR Signaling Pathway
  • P38 MAPK Signaling Pathway
    P38 MAPK Signaling Pathway
参考文献
  • Ding X, et al., 2009, PLoS One. 4(6): e5949.
  • Ratsima H, et al., 2011, Proc Natl Acad Sci. 108(43): E914-23.
  • Chiang YJ, et al., 2013, PLoS One. 8(4): e61761.
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