Cytokeratin 5/KRT5 Lentiviral cDNA ORF Clone, Human, C-GFPSpark® tag

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Cytokeratin 5/KRT5 Lentiviral cDNA ORF Clone, Human, C-GFPSpark® tag: 产品信息

基因
种属
Human
NCBI 参考序列号
基因长度
1773 bp
序列特征
Identical with the Gene Bank Ref. ID sequence (Nucleotide may contain silent mutation without changing amino acid sequence)
产品特征
Full length Clone DNA of Homo sapiens keratin 5.
质粒
启动子
Enhanced CMV mammalian cell promoter
标签序列
GFPSpark Tag Sequence: GTGAGCAAGGGC……GAGCTGTACAAG
测序引物
pLen-F(CTCGTTTAGTGAACCGTCAGAATT), pLen-R(GAACCGGAACCCTTAAACATGT)
质控
The plasmid is confirmed by full-length sequencing.
筛选
细菌筛选抗性
Ampicillin
储存 & 运输
运输方式
Each tube contains 10μg lyophilized plasmid
储存条件
The lyophilized plasmid can be stored at room temperature for three months

Cytokeratin 5/KRT5 Lentiviral cDNA ORF Clone, Human, C-GFPSpark® tag: 别称

CK5 cDNA ORF Clone, Human; DDD cDNA ORF Clone, Human; DDD1 cDNA ORF Clone, Human; EBS2 cDNA ORF Clone, Human; K5 cDNA ORF Clone, Human; KRT5A cDNA ORF Clone, Human

Cytokeratin 5/KRT5 背景信息

Keratin 5 is the major type II keratin of the basal cells of epidermis and of other stratified epithelia. With its type I partner, keratin 14, it constitutes a major fraction of the cytoskeleton of the basal cells. Epidermolysis bullosa simplex with mottled pigmentation (EBS-MP) is a rare dermatologic disorder of autosomal dominant inheritance with intraepidermal blistering after minor trauma, reticular hyperpigmentation unrelated to the blistering, nail dystrophy, and mild palmoplantar keratosis. Keratin 5 and keratin 14 are known to be essential for the basal keratinocyte cytoskeleton and are defective in several forms of epidermolysis bullosa simplex. Recently, a 71C-->T transition in the keratin 5 gene (KRT5) causing a P24L substitution was identified in some patients with EBS-MP.
全称
keratin 5, type II
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