MEK3/MKK3 cDNA ORF Clone, Human, untagged

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MEK3/MKK3 cDNA ORF Clone, Human, untagged: 产品信息

基因
种属
Human
NCBI 参考序列号
基因长度
957 bp
序列特征
Identical with the Gene Bank Ref. ID sequence.
产品特征
Full length Clone DNA of Human mitogen-activated protein kinase kinase 3.
质粒
启动子
Enhanced CMV promoter
限制性酶切位点
KpnI + XbaI(6.1kb+0.96kb)
测序引物
T7( 5' TAATACGACTCACTATAGGG 3' ) BGH( 5' TAGAAGGCACAGTCGAGG 3' )
质控
The plasmid is confirmed by full-length sequencing.
筛选
细菌筛选抗性
Ampicillin
细胞筛选抗性
Hygromycin
应用
Stable or Transient mammalian expression
储存 & 运输
运输方式
Each tube contains lyophilized plasmid.
储存条件
The lyophilized plasmid can be stored at ambient temperature for three months.

MEK3/MKK3 cDNA ORF 核苷酸序列及氨基酸序列信息

**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**

关于 MEK3/MKK3的更多信息

Entrez Gene ID

MEK3/MKK3 cDNA ORF Clone, Human, untagged: 验证图片

MEK3/MKK3 cDNA ORF Clone, Human, untagged: 别称

MAPKK3 cDNA ORF Clone, Human; MEK3 cDNA ORF Clone, Human; MKK3 cDNA ORF Clone, Human; PRKMK3 cDNA ORF Clone, Human; SAPKK-2 cDNA ORF Clone, Human; SAPKK2 cDNA ORF Clone, Human

MEK3/MKK3 背景信息

MAP2K3 (Mitogen-Activated Protein Kinase Kinase 3, also known as MKK3) is a Protein Coding gene. The protein encoded by this gene is a dual-specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic and environmental stress and participates in the MAP kinase-mediated signaling cascade. 3 alternatively spliced human isoforms have been reported. MAP2K3 is widely expressed in bone marrow, gall bladder, and other tissues. MAP2K3 resides in a biological pathway linked to memory. It is in a signaling cascade associated with beta-amyloid mediated apoptosis and has enriched expression in microglia.MAP2K3 may represent a novel therapeutic target for age-related memory decline and perhaps Alzheimer's disease (AD).
全称
mitogen-activated protein kinase kinase 3
Related Pathways
  • Death Receptor Signaling
    Death Receptor Signaling
  • Non-Canonical Wnt Pathway
    Non-Canonical Wnt Pathway
  • TGF-beta Signaling
    TGF-beta Signaling
  • TNF Signaling
    TNF Signaling
  • VEGF Signaling Pathway
    VEGF Signaling Pathway
  • Actin Dynamics Signaling Pathway
    Actin Dynamics Signaling Pathway
  • B Cell Receptor Signaling Pathway
    B Cell Receptor Signaling Pathway
  • G Protein-coupled Receptors Signaling
    G Protein-coupled Receptors Signaling
  • Jak-Stat Signaling Pathway
    Jak-Stat Signaling Pathway
  • P38 MAPK Signaling Pathway
    P38 MAPK Signaling Pathway
  • Common G-Chain signaling pathway
    Common G-Chain signaling pathway
  • IL1 signaling pathway
    IL1 signaling pathway
  • IL17 signaling pathway
    IL17 signaling pathway
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