OPA3 cDNA ORF Clone in Cloning Vector, Human

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OPA3 cDNA ORF Clone in Cloning Vector, Human: 产品信息

基因
种属
Human
NCBI 参考序列号
基因长度
540 bp
序列特征
Identical with the Gene Bank Ref. ID sequence.
产品特征
Full length Clone DNA of Human OPA3, outer mitochondrial membrane lipid metabolism regulator
质粒
载体
测序引物
M13-47 and RV-M
质控
The plasmid is confirmed by full-length sequencing.
筛选
细菌筛选抗性
Ampicillin
储存 & 运输
运输方式
Each tube contains lyophilized plasmid.
储存条件
The lyophilized plasmid can be stored at ambient temperature for three months.

OPA3 cDNA ORF 核苷酸序列及氨基酸序列信息

**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**

关于 OPA3的更多信息

Entrez Gene ID

OPA3 cDNA ORF Clone in Cloning Vector, Human: 别称

MGA3 cDNA ORF Clone, Human; OPA3 cDNA ORF Clone, Human

OPA3 背景信息

The OPA3 protein is enriched in the inner mitochondrial membrane and has mitochondrial targeting signals. Costeff Syndrome, which is caused by mutations in the OPTIC ATROPHY 3 (OPA3) gene, is an early-onset syndrome characterized by urinary excretion of 3-methylglutaconic acid (MGC), optic atrophy and movement disorders, including ataxia and extrapyramidal dysfunction. At least four mutations in the OPA3 gene have been found to cause autosomal dominant optic atrophy and cataract.
参考文献
  • Pei W, et al. (2010) A model of costeff syndrome reveals metabolic and protective functions of mitochondrial opa3. Development 137 (15): 2587-2596.
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