The plasmid is confirmed by full-length sequencing.
储存 & 运输
Each tube contains lyophilized plasmid.
The lyophilized plasmid can be stored at ambient temperature for three months.
OPA3 cDNA ORF 核苷酸序列及氨基酸序列信息
**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**
MGA3 cDNA ORF Clone, Human; OPA3 cDNA ORF Clone, Human
The OPA3 protein is enriched in the inner mitochondrial membrane and has mitochondrial targeting signals. Costeff Syndrome, which is caused by mutations in the OPTIC ATROPHY 3 (OPA3) gene, is an early-onset syndrome characterized by urinary excretion of 3-methylglutaconic acid (MGC), optic atrophy and movement disorders, including ataxia and extrapyramidal dysfunction. At least four mutations in the OPA3 gene have been found to cause autosomal dominant optic atrophy and cataract.
Pei W, et al. (2010) A model of costeff syndrome reveals metabolic and protective functions of mitochondrial opa3. Development 137 (15): 2587-2596.